Die Studie

Clinical trial of a new compound that is being developed for the treatment of Alzheimer’s Disease.

  • You are a healthy male or female
  • You are between 18 and 45 years old
  • Your Body Mass Index (BMI) is between 18 and 32 kg/m2.
  • Both non-smokers and light smokers or occasional smokers are allowed to participate in this clinical trial. However, smoking is not allowed during your stay in the research facility

Note: 

  • You cannot participate in the trial if you have participated in another clinical trial in the 90 days prior to the first administration in this clinical trial (counting from the follow-up visit). For some trials this will be 6 months, this will be discussed during your telephone screening.
  • For this trial, you cannot (have) receive(d) a COVID-19 vaccine within 6 weeks prior to the start and during this trial.
  • Part 1a/b To determine if you are suitable to participate in this trial, you will undergo a medical screening. Depending on availability, this can be performed in Groningen or in Utrecht.

As a female you can only participate if you are not pregnant and not breast feeding and meet one of the following conditions:

  • You are using a copper intra-uterine device in combination with a condom;
  • You have passed the menopause (no menses for at least 12 months);
  • You have been sterilized with one of the following methods: hysterectomy, fallopian tube removal or ovary removal;
  • You have been sterilized by tubal ligation and you are using a condom;
  • Your male partner has been sterilized and you are using a condom;
  • You have been sterilized or your male partner has been sterilized and you are using a condom;
  • You are not heterosexually active according to your lifestyle.

As a male you can only participate if you meet one of the following conditions:

  • You are using a condom in combination with a contraception method used by your female partner;
  • You have been sterilized and you are using a condom
  • Your female partner is sterilized by means of a hysterectomy, fallopian tube removal or ovary removal or is postmenopausal;
  • Your female partner is sterilized by means of tubal ligation and you are using a condom;
  • You are not heterosexually active according to your lifestyle.

Zeitraum

The trial consists of 3 parts with each multiple groups. You can only participate in one part and one group.

  • Part 1a: The trial consists of 1 period during which you will stay in the research facility in Groningen for 6 days 5 nights), followed by 1 short visit. The follow-up visit will take place 2 - 6 days after your short visit.
Group A7c  

6 Tage Aufenthalt

 
  • 9 Okt 2022 bis einschl. 14 Okt 2022
 

kurzer Besuch

 
  • 16 Okt 2022
 

Nachuntersuchung

 
  • Nach Vereinbarung zwischen 18 Okt 2022 bis einschl. 22 Okt 2022
 

 

Group A7b  

6 Tage Aufenthalt

 
  • 17 Okt 2022 bis einschl. 22 Okt 2022
 

kurzer Besuch

 
  • 24 Okt 2022
 

Nachuntersuchung

 
  • Nach Vereinbarung zwischen 26 Okt 2022 bis einschl. 30 Okt 2022
 

Aufwandsentschädigung

  • You will receive a gross compensation of € 1323 for participation in one of the groups of part 1a.

Travel expenses will be reimbursed based on the distance traveled (€ 0,19 net per kilometer) with a minimum of € 12 and a maximum of € 160 (840 kilometers) per round trip, regardless of the mode of transportation