Die Studie

Study of an investigational compound that is being developed for the treatment of Parkinson’s disease.

  • You must speak and understand English or Dutch to participate.
  • For this study we are looking for healthy males and females, between 18 and 50 years old who do not smoke.
  • Your Body Mass Index (BMI) is between 18.5 and 32 kg/m2 and your body weight is at least 50 kilograms. The BMI shows the relation between body weight in kilograms and height in meters.
  • Males are only allowed to participate if you use sufficient contraception or have been sterilized.
  • Females are only allowed to participate in this study if you:  
    • Have been sterilized for at least 6 months before the screening (Essure® method is not allowed for this study)
    • Have been postmenopausal for at least 12 months (without menstrual periods).
  • To determine if you are suitable to participate in this study, you will undergo a medical screening visit.
  • You are only allowed to participate, if you did not participate in a drug study within the 60 days prior to the screening for this study.
  • You are willing to perform a pulmonary function test as part of the screening (separate visit) and during the study.
  • You are willing to undergo two lumbar punctures during the study.


For Part E, the study consists of 1 period during which you will stay in our research facility in Groningen for 19 days (18 nights). Finally, there will be a follow-up visit including a pulmonary function test between 4 and 10 days after discharge from the research facility.

Please note: it may happen that the pulmonary function test takes place on a day other than the follow-up visit.

Group 19 days stay follow-up
E1c 19 feb t/m 8 mrt 2020 16 mrt 2020
E2a 1 t/m 19 apr 2020 27 apr 2020
E2b 15 apr t/m 3 mei 2020 11 mei 2020
E2c 22 apr t/m 10 mei 2020 18 mei 2020

You can find the exact dates of each group on our website. If the dates do change you will be notified as soon as possible.


You will receive a gross compensation of € 3423 for participation in any of the groups of Part E.

Travelling expenses will be reimbursed based on the distance traveled (€0.19 net per kilometer) with a minimum of €12 and a maximum of €160 (840 kilometers) per return, regardless of the mode of transportation.